Household Glassware Machinery

Ampoule Filling & Sealing Machine

ModelSM-J40

Complete guide to Sea Melody ampoule filling and sealing machines — 2, 4, 6, and 8-needle models compared. Rectangular feeding system, PLC control, 1–20ml ampoules. Choose the right model for your production scale.

Needle Options: 2 / 4 / 6 / 8Output: 1,800–16,000 pcs/hAmpoule Size: 1–20mlFuel: Gas / LPGControl: PLC + Touch Screen

Ampoule Filling & Sealing Machines — Full Range

An ampoule filling and sealing machine is an automated system that doses liquid medication into glass ampoules and then hermetically seals each ampoule with a high-temperature flame, producing sterile, tamper-proof units ready for pharmaceutical packaging.

Sea Melody’s ampoule filling and sealing machines are combined drawing, filling, and sealing systems designed for pharmaceutical-grade ampoule production. All models share the same core technology: a rectangular feeding system that replaces the traditional rotating turntable, delivering higher filling precision, reduced ampoule breakage, and consistent production output across high-speed runs.

Available in four needle configurations — 2, 4, 6, and 8 needles — each model is suited to a different production scale. This page helps you choose the right model. If you already know your needle count, jump directly to the model page below.

How to Choose the Right Model

The needle count determines how many ampoules are filled simultaneously per cycle. Higher needle count = higher output per hour, larger machine footprint, and more power consumption. The right choice depends on your daily production target, ampoule size, and floor space.

Model Needles Output (pcs/h) Ampoule Size Power Best For View
SM-J39 2 needles 1,800 – 4,200 5 – 20ml 0.37 kW Small-batch, pilot lines, or larger ampoule sizes (10–20ml) SM-J39 →
SM-J40 4 needles 6,000 – 10,000 1 – 20ml 0.73 kW Mid-scale production, versatile across 1–20ml range ↓ Specs below
SM-J41 6 needles 8,100 – 12,000 1 – 20ml 0.55 – 0.75 kW Most popular — balanced output and efficiency for standard pharma lines SM-J41 →
SM-J42 8 needles 12,000 – 16,000 1 – 20ml 0.75 – 1.5 kW High-volume production lines, 1–10ml ampoules at maximum throughput SM-J42 →

Not sure which output level you need? Contact us with your daily production target and ampoule size — our engineers will recommend the right model.

Features Across All Models

  • Rectangular feeding system — feeds ampoules in a straight line rather than on a rotating turntable, reducing breakage and improving fill consistency
  • Combined process — drawing, filling, and sealing in one continuous automated sequence
  • PLC intelligent control with touch screen interface — all models
  • 304 stainless steel product-contact parts, FDA compliant
  • Automatic no-ampoule / no-fill detection — machine stops filling if an ampoule is missing or misaligned
  • Optional nitrogen gas blanketing before and after filling — for oxygen-sensitive injectables
  • Handles 1ml to 20ml ampoules across the range (SM-J39 starts at 5ml)
  • Compatible with pipeline gas (LPG), liquefied natural gas, or gasified gasoline as sealing fuel

Technical Specifications

Parameter Value
Needles 4
Output 6,000 – 10,000 pcs/h (1–2ml: up to 10,000; 5–10ml: up to 8,000)
Ampoule Sizes 1ml, 2ml, 5ml, 10ml, 20ml
Power 380V / 0.73 kW
Fuel Consumption 2–2.5 m³/h gas / LPG
Machine Dimensions 1,650 × 900 × 1,500 mm
Weight 300 kg
Contact Parts 304 stainless steel — FDA compliant

Applications

  • Pharmaceutical injection ampoule filling and sealing
  • Vaccine and biologic ampoule packaging
  • Cosmetic serum and essence ampoules
  • Chemical reagent ampoule sealing
  • Veterinary medicine ampoule production
  • IV solution and saline ampoule filling

Product Demo

Product demonstration video coming soon. Visit our YouTube channel to see Sea Melody machines in action.

Frequently Asked Questions

What is the difference between 2, 4, 6, and 8 needle models?

The needle count determines how many ampoules are filled simultaneously per machine cycle. More needles = higher hourly output. The 2-needle SM-J39 suits small or pilot-scale production; the 6-needle SM-J41 is the most popular for standard pharma lines; the 8-needle SM-J42 is for high-volume continuous production. All models share the same rectangular feeding system and PLC control platform.

Can the same machine handle different ampoule sizes?

Yes — all models handle multiple ampoule sizes (1ml to 20ml depending on model). Changeovers between sizes require adjusting the feed hopper, tooth plate, and needle group, guided by the supplied operation and adjustment manual. The SM-J39 starts at 5ml; all other models handle from 1ml.

What fuel does the sealing system use?

The sealing burners are compatible with pipeline gas, LPG (liquefied petroleum gas), and liquefied natural gas. Gasified gasoline is also supported with a replacement burner head and pressure stabilizer. Oxygen is used as the combustion support gas across all fuel types.

Is nitrogen gas protection available?

Yes — all models support optional nitrogen gas blanketing during the filling step. This displaces oxygen from the ampoule before sealing and is standard practice for injectable medications and oxygen-sensitive chemical reagents.

Can Sea Melody customise the machine for non-standard requirements?

Yes — needle count, ampoule size range, filling volume, and feed system parameters can all be modified. Visit our Custom Orders page to discuss your specification with our engineering team.

What after-sales support is provided?

All machines include remote commissioning support via live video, a full operation and maintenance manual, and 7×24 after-sales service. Our after-sales engineers are assigned per machine before shipment, so they are familiar with your specific configuration. See our After-Sales Support page for full details.

Is the Ampoule Filling & Sealing Machine CE certified?

Yes. Sea Melody manufactures under an ISO 9001:2015-certified quality management system, and this machine is built to meet CE requirements for export markets. Quality and compliance certificates are provided on request and during the quotation process.

Who manufactures this machine?

This machine is designed and manufactured by Nantong Sea Melody Industrial Co., Ltd, a specialist glass machinery manufacturer based in Nantong, China, with over 24 years of experience. Sea Melody machines are currently operating in 35+ countries across pharmaceuticals, laboratory, and household glassware industries. Learn more about Sea Melody →

Interested in This Machine?

Our team can provide full specs, custom configurations, and fast quotes. We ship to 35+ countries.